CRE & ESBL
A selection of clinically relevant panels that detect resistance markers of enterobacteriaceae which commonly cause infections within healthcare and community settings. High spread levels of extended spectrum β-lactamases (ESBL) make testing for resistance increasingly necessary, since carbapenems are one of the few remaining antibiotics that can combat ESBL-producing pathogens. Although mostly effective, resistance enzymes (carbapenemases) that destroy these antibiotics pose serious public health concern.
These panels detect a representative selection of simple β-lactamases, extended spectrum β-lactamases (ESBL) and carbapenemases. The selection of targets in each panel reflects the prevalence of ESBL or CRE in different geographical regions.
These panels detect a representative selection of simple β-lactamases, extended spectrum β-lactamases (ESBL) and carbapenemases. The selection of targets in each panel reflects the prevalence of ESBL or CRE in different geographical regions.
CRE 16-well (REF 21098)
Carbapenemases
- NDM
- KPC
- IMP (1, 4, 5, 6, 10, 14a)
- VIM
- OXA-23-like
- OXA-48-like
- OXA-51-like
- OXA-58-like
- IMI
- SME
Extended Spectrum β-lactamases (ESBL’s)
- CMY
- GES
- CTX-M group 1
- CTX-M group 9
Internal control
- Bacteria 16S RNA
Ordering Information
Ref
Description
Pack size
Tests
21098S
CRE 16-well Step 1 Tubes
12 x 8-well Strips
96
21098P
CRE 16-well Step 2 Plates
Box of 12 Plates
288
40231
Low DNA Reagent Cassette*
Box of 10
-
40421
Medium DNA Reagent Reservoir**
Box of 4
-
91151
Synthetic Positive Control for Bacteria and Bacterial Resistance
Box of 10
-
CRE EU 16-well (REF 21099)
Carbapenemases
- NDM
- KPC
- IMP (1, 4, 5, 6, 8, 10, 14a)
- VIM
- OXA-48-like
- IMI
- SME
- GIM-1
- FRI-1
- SIM-1
- SPM-1
Extended Spectrum β-lactamases (ESBL’s)
- GES
Other resistance markers
- Colistin resistance MCR-1
Ordering Information
Ref
Description
Pack size
Tests
21099S
CRE EU 16-well Step 1 Tubes
12 x 8-well Strips
96
21099P
CRE EU 16-well Step 2 Plates
Box of 12 Plates
288
40231
Low DNA Reagent Cassette*
Box of 10
-
40421
Medium DNA Reagent Reservoir**
Box of 4
-
91151
Synthetic Positive Control for Bacteria and Bacterial Resistance
Box of 10
-
CRE Reference 24-well (REF 81099)
Carbapenemases
- NDM
- KPC
- IMP (1, 4, 5, 6, 8, 10, 14a)
- VIM
- OXA-23-like
- OXA-24/40-like
- OXA-48-like
- OXA-51-like
- OXA-58-like
- IMI
- SME
- DIM-1
- GIM-1
- FRI-1
- SIM-1
- SPM-1
Extended Spectrum β-lactamases (ESBL’s)
- GES
- PER-1
- VEB-1
Other resistance markers
- Colistin resistance MCR-1
- KPC mutation D179Y
Ordering Information
Ref
Description
Pack size
Tests
81099S
CRE Reference 24-well Step 1 Tubes
12 x 8-well Strips
96
81099P
CRE Reference 24-well Step 2 Plates
Box of 12 Plates
192
40231
Low DNA Reagent Cassette*
Box of 10
-
40421
Medium DNA Reagent Reservoir**
Box of 4
-
91151
Synthetic Positive Control for Bacteria and Bacterial Resistance
Box of 10
-
ESBL 16-well (REF 21093)
β-lactamases
- pan-SHV
- pan-TEM
- pan-CMY
Extended Spectrum β-lactamases (ESBL’s)
- DHA-1
- CTX-M group 1
- CTX-M group 9
Carbapenemases
- NDM
- KPC
- IMP (1, 4, 5, 6, 10, 14a)
- VIM
- OXA-1-like
- OXA-48-like
- VEB-1
Internal control
- Bacteria 16S RNA
Ordering Information
Ref
Description
Pack size
Tests
21093S
ESBL 16-well Step 1 Tubes
12 x 8-well Strips
96
21093P
ESBL 16-well Step 2 Plates
Box of 12 Plates
288
40231
Low DNA Reagent Cassette*
Box of 10
-
40421
Medium DNA Reagent Reservoir**
Box of 4
-
91151
Synthetic Positive Control for Bacteria and Bacterial Resistance
Box of 10
-
Gram Positive Resistance
A select panel of gram-positive pathogens that are a common cause of wound infections, urinary tract infections (UTIs), and sepsis in addition to their antimicrobial resistance markers.
Staphylococcus + VRE 8-well (REF 21340)
Gram positive bacteria
- Enterococcus faecium
- Enterococcus faecalis
- Staphylococcus aureus
Methicillin resistance
- mecA
- femA
Vancomycin resistance
- vanA
- vanB
Ordering Information
Ref
Description
Pack size
Tests
21340S
Staphylococcus + VRE 8-well Step 1 Tubes
12 x 8-well Strips
96
21340P
Staphylococcus + VRE 8-well Step 2 Plates
Box of 12 Plates
288
40241
Demi DNA Reagent Cassette
Box of 10
-
91151
Synthetic Positive Control for Bacteria and Bacterial Resistance
Box of 10
-
Fungal Identification
Detailed screening of 17 fungal candidates associated with systemic fungal infections, skin infection, osteomyelitis, fungemia, and endophthalmitis.
Fungal ID 16-well (REF 24110) (RUO)
- Candida albicans
- Candida glabrata
- Candida parapsilosis
- Pichia kudriavzevii (Candida krusei)
- Candida dubliniensis
- Meyerozyma guiliermondii (Candida guiliermondii)
- Debaryomyces hansenii (Candida famata)
- Candida auris
- Candida tropicalis
- Candida kefyr
- Fusarium spp.
- Fusarium solani
- Lomentospora prolificans (Scedosporium prolificans)
- Cryptococcus neoformans and C. gattii
- Saccharomyces cerevisiae
- Yarrowia lipolytica
- Aspergillus spp.
Ordering Information
Ref
Description
Pack size
Tests
24110S
Fungal ID 16-well Step 1 Tubes
12 x 8-well Strips
96
24110P
Fungal ID 16-well Step 2 Plates
Box of 12 Plates
288
40231
Low DNA Reagent Cassette*
Box of 10
-
40421
Medium DNA Reagent Reservoir**
Box of 4
-
91091
Synthetic Positive Controls for Fungal Panels
Box of 10
-
Encephalitis, Meningitis, & Herpes
Analysis of cerebrospinal fluid (CSF) is crucial for the diagnosis and management of central nervous system (CNS) infections. Molecular methods for the detection and identification of bacterial and viral pathogens have demonstrated value for patients with clinical symptoms consistent with CNS infection.
Syndromic testing panels that detect bacteria which are likely to infect the CNS such as Haemophilus influenzae, Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes or Escherichia coli are recommended.
PCR has also become the standard for detecting viruses associated with aseptic meningitis or encephalitis especially for Enterovirus and Parechovirus. Depending on the age and immune status of the patient, there are many other viruses which can cause infection. These include Herpes Simplex Virus (HSV), Varicella Zoster Virus (VZV), Cytomegalovirus (CMV), Human Herpesvirus 6 (HHV-6), Epstein-Barr Virus (EBV), Enterovirus (EV), and human Parechovirus (HPeV).
Syndromic testing panels that detect bacteria which are likely to infect the CNS such as Haemophilus influenzae, Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes or Escherichia coli are recommended.
PCR has also become the standard for detecting viruses associated with aseptic meningitis or encephalitis especially for Enterovirus and Parechovirus. Depending on the age and immune status of the patient, there are many other viruses which can cause infection. These include Herpes Simplex Virus (HSV), Varicella Zoster Virus (VZV), Cytomegalovirus (CMV), Human Herpesvirus 6 (HHV-6), Epstein-Barr Virus (EBV), Enterovirus (EV), and human Parechovirus (HPeV).
CSF 16-well (REF 27050)
Bacteria
- Haemophilus influenzae
- Neisseria meningitidis – 2 assays
- Streptococcus pneumoniae
- Listeria monocytogenes (LMO)
- Leptospira interrogans
- Mycobacterium tuberculosis complex
Viruses
- HSV-1 (Human herpesvirus 1)
- HSV-2 (Human herpesvirus 2)
- VZV (Human herpesvirus 3)
- EBV (Human herpesvirus 4)
- Enterovirus
- Parechovirus
Fungi
- Cryptococcus neoformans and C. gatti
Ordering Information
Ref
Description
Pack size
Tests
27050S
CSF 16-well Step 1 Tubes
12 x 8-well Strips
96
27050P
CSF 16-well Step 2 Plates
Box of 12 Plates
288
40331
Low RNA Reagent Cassette*
Box of 10
-
40521
Medium RNA Reagent Reservoir**
Box of 4
-
91081
Synthetic Positive Controls for CSF
Box of 10
-
CSF 24-well (REF 87024) (RUO)
Bacteria
- Neisseria meningitidis – 2 assays
- Haemophilus influenzae
- Streptococcus pneumoniae
- Streptococcus agalactiae
- Escherichia coli
- Listeria monocytogenes (LMO)
- Leptospira interrogans
- Mycobacterium tuberculosis complex
- Staphylococcus aureus
- Staphylococcus spp.
- Kingella kingae
Viruses
- HSV-1 (Human herpesvirus 1)
- HSV-2 (Human herpesvirus 2)
- VZV (Human herpesvirus 3)
- EBV (Human herpesvirus 4)
- CMV (Human herpesvirus 5)
- HHV-6 (Human herpesvirus 6)
- Enterovirus
- Parechovirus
Fungi
- Cryptococcus neoformans and C. gatti
Resistance genes
- Methicillin resistance mecA
- Methicillin resistance femA
Ordering Information
Ref
Description
Pack size
Tests
87024S
CSF 24-well Step 1 Tubes
12 x 8-well Strips
96
87024P
CSF 24-well Step 2 Plates
Box of 12 Plates
192
40331
Low RNA Reagent Cassette*
Box of 10
-
40521
Medium RNA Reagent Reservoir**
Box of 4
-
91081
Synthetic Positive Controls for CSF
Box of 10
-
Find the best panel for your needs
TandemPlex® panels are intended for in vitro diagnostics use by authorised clinical testing laboratories in Australia, New Zealand, and the European Economic Area and is included on the Australian Register of Therapeutic Goods (ARTG), and compliant with the European IVD Directive 98/79/EC. Research use only in USA.
